![American Airlines flights from Greenville to Mexico](https://assets.airtrfx.com/media-em/aa/6230df2d8ca50_puerto_vallarta.jpg?width=1200&quality=80&fit=crop&format=auto&opt=true)
American Airlines flights from Greenville to Mexico
Popular flights with American Airlines
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Travel Class
*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.
![American Airlines flights from Greenville to Mexico](https://assets.airtrfx.com/media-em/aa/6230df2d8ca50_puerto_vallarta.jpg?width=1200&quality=80&fit=crop&format=auto&opt=true)
Find more Greenville to Mexico deals
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Travel Class
Greenville (GSP)to
Cancun (CUN)
06/03/25 - 06/10/25
Round trip
I
Economy
from
$454*
Updated: 3 hours ago
Greenville (GSP)to
Mexico City (MEX)
05/01/25 - 05/08/25
Round trip
I
Economy
from
$537*
Updated: 3 hours ago
Greenville (GSP)to
Cabo San Lucas (SJD)
04/09/25 - 04/16/25
Round trip
I
Economy
from
$487*
Updated: 11 hours ago
Greenville (GSP)to
Cozumel (CZM)
05/13/25 - 05/20/25
Round trip
I
Economy
from
$472*
Updated: 1 hour ago
Greenville (GSP)to
Puerto Vallarta (PVR)
03/18/25 - 03/25/25
Round trip
I
Economy
from
$555*
Updated: 1 hour ago
Greenville (GSP)to
Queretaro (QRO)
03/10/25 - 03/17/25
Round trip
I
Economy
from
$470*
Updated: 7 hours ago
*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.