Flights from Panama City with American Airlines

Popular flights from Panama City

$
Travel Class

  • Panama City (ECP)to

    Seattle (SEA)
    01/08/25 - 01/15/25
    from
    $378*
    Updated: 1 hour ago
    Round trip
    I
    Economy

    Panama City (ECP)to

    Oklahoma City (OKC)
    12/25/24 - 01/01/25
    from
    $296*
    Updated: 1 hour ago
    Round trip
    I
    Economy

    Panama City (ECP)to

    Saint Louis (STL)
    01/07/25 - 01/14/25
    from
    $356*
    Updated: 1 hour ago
    Round trip
    I
    Economy

    Panama City (ECP)to

    Boston (BOS)
    12/24/24 - 12/31/24
    from
    $326*
    Updated: 2 hours ago
    Round trip
    I
    Economy

  • Panama City (ECP)to

    Denver (DEN)
    01/07/25 - 01/14/25
    from
    $288*
    Updated: 4 hours ago
    Round trip
    I
    Economy

    Panama City (ECP)to

    Detroit (DTW)
    12/24/24 - 12/31/24
    from
    $306*
    Updated: 13 minutes ago
    Round trip
    I
    Economy

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

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Find deals on flights from Panama City

$
Travel Class

Panama City (ECP)to

Charlotte (CLT)
01/18/25 - 01/25/25

Round trip

I

Economy

from
$233*
Updated: 4 hours ago

Panama City (ECP)to

Washington, D.C. (DCA)
02/15/25 - 02/22/25

Round trip

I

Economy

from
$223*
Updated: 15 hours ago

Panama City (ECP)to

Fort Lauderdale (FLL)
01/18/25 - 01/25/25

Round trip

I

Economy

from
$256*
Updated: 8 hours ago

Panama City (ECP)to

Cleveland (CLE)
02/15/25 - 02/22/25

Round trip

I

Economy

from
$306*
Updated: 1 hour ago

Panama City (ECP)to

Seattle (SEA)
02/18/25 - 02/25/25

Round trip

I

Economy

from
$378*
Updated: 1 hour ago

Panama City (ECP)to

Oklahoma City (OKC)
01/18/25 - 01/25/25

Round trip

I

Economy

from
$296*
Updated: 1 hour ago

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

Destinations from Panama City

Explore American Airlines's Top-Pick Destinations