Flights from San Diego with American Airlines

Popular flights from San Diego

$

  • San Diego (SAN)to

    Tokyo (TYO)
    03/18/25 - 03/25/25
    from
    $1,006*
    Updated: 2 hours ago
    Round trip
    I
    Economy

    San Diego (SAN)to

    Phoenix (PHX)
    04/09/25 - 04/16/25
    from
    $117*
    Updated: 3 hours ago
    Round trip
    I
    Economy

    San Diego (SAN)to

    Charlotte (CLT)
    04/07/25 - 04/14/25
    from
    $277*
    Updated: 3 hours ago
    Round trip
    I
    Economy

    San Diego (SAN)to

    London (LHR)
    04/07/25 - 04/16/25
    from
    $669*
    Updated: 16 hours ago
    Round trip
    I
    Economy

  • San Diego (SAN)to

    Boston (BOS)
    04/09/25 - 04/16/25
    from
    $287*
    Updated: 4 hours ago
    Round trip
    I
    Economy

    San Diego (SAN)to

    Orlando (MCO)
    04/09/25 - 04/16/25
    from
    $275*
    Updated: 3 hours ago
    Round trip
    I
    Economy

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

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To search for a great fare, start by selecting your departure city. Looking to book using miles? Try our miles finder map.

Find deals on flights from San Diego

$

San Diego (SAN)to

Dallas (DFW)
05/13/25 - 05/20/25

Round trip

I

Economy

from
$179*
Updated: 3 hours ago

San Diego (SAN)to

Philadelphia (PHL)
05/12/25 - 05/19/25

Round trip

I

Economy

from
$311*
Updated: 3 hours ago

San Diego (SAN)to

Miami (MIA)
05/13/25 - 05/20/25

Round trip

I

Economy

from
$237*
Updated: 3 hours ago

San Diego (SAN)to

Chicago (ORD)
04/19/25 - 04/20/25

Round trip

I

Economy

from
$278*
Updated: 12 hours ago

San Diego (SAN)to

Tokyo (TYO)
01/06/26 - 01/21/26

Round trip

I

Economy

from
$827*
Updated: 16 hours ago

San Diego (SAN)to

Phoenix (PHX)
04/29/25 - 05/06/25

Round trip

I

Economy

from
$117*
Updated: 3 hours ago

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

Destinations from San Diego

Explore American Airlines's Top-Pick Destinations