Flights to Cayman Islands with American Airlines

Popular flights with American Airlines

  • Charlotte (CLT)to

    Grand Cayman (GCM)
    05/06/25 - 05/13/25
    from
    $535*
    Updated: 1 hour ago
    Round trip
    I
    Economy

    Charlotte (CLT)to

    Grand Cayman (GCM)
    05/07/25 - 05/14/25
    from
    $535*
    Updated: 1 hour ago
    Round trip
    I
    Economy

    Philadelphia (PHL)to

    Grand Cayman (GCM)
    05/14/25 - 05/21/25
    from
    $600*
    Updated: 1 hour ago
    Round trip
    I
    Economy

    Philadelphia (PHL)to

    Grand Cayman (GCM)
    05/07/25 - 05/14/25
    from
    $600*
    Updated: 1 hour ago
    Round trip
    I
    Economy

  • Chicago (ORD)to

    Grand Cayman (GCM)
    05/07/25 - 05/14/25
    from
    $610*
    Updated: 1 hour ago
    Round trip
    I
    Economy

    Chicago (ORD)to

    Grand Cayman (GCM)
    05/14/25 - 05/21/25
    from
    $610*
    Updated: 1 hour ago
    Round trip
    I
    Economy

    Boston (BOS)to

    Grand Cayman (GCM)
    03/19/25 - 03/26/25
    from
    $292*
    Updated: 1 hour ago
    Round trip
    I
    Economy

    Boston (BOS)to

    Grand Cayman (GCM)
    03/26/25 - 04/02/25
    from
    $292*
    Updated: 1 hour ago
    Round trip
    I
    Economy

  • Pittsburgh (PIT)to

    Grand Cayman (GCM)
    03/17/25 - 03/24/25
    from
    $484*
    Updated: 45 minutes ago
    Round trip
    I
    Economy

    Pittsburgh (PIT)to

    Grand Cayman (GCM)
    03/20/25 - 03/27/25
    from
    $484*
    Updated: 45 minutes ago
    Round trip
    I
    Economy

    Kansas City (MCI)to

    Grand Cayman (GCM)
    03/19/25 - 03/26/25
    from
    $484*
    Updated: 2 hours ago
    Round trip
    I
    Economy

    Kansas City (MCI)to

    Grand Cayman (GCM)
    03/20/25 - 03/27/25
    from
    $484*
    Updated: 2 hours ago
    Round trip
    I
    Economy

  • Columbus (CMH)to

    Grand Cayman (GCM)
    03/13/25 - 03/20/25
    from
    $484*
    Updated: 8 hours ago
    Round trip
    I
    Economy

    Los Angeles (LAX)to

    Grand Cayman (GCM)
    03/19/25 - 03/26/25
    from
    $518*
    Updated: 1 hour ago
    Round trip
    I
    Economy

    Los Angeles (LAX)to

    Grand Cayman (GCM)
    03/20/25 - 03/27/25
    from
    $518*
    Updated: 1 hour ago
    Round trip
    I
    Economy

    Phoenix (PHX)to

    Grand Cayman (GCM)
    03/19/25 - 03/26/25
    from
    $656*
    Updated: 1 hour ago
    Round trip
    I
    Economy

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

Flights to the Cayman Islands with American Airlines

Business Class flights to Cayman Islands 

Dallas (DFW)to

Grand Cayman (GCM)
05/10/25 - 05/17/25

Round trip

I

Business / First

from
$1,255*
Updated: 4 hours ago

Miami (MIA)to

Grand Cayman (GCM)
02/28/25 - 03/03/25

Round trip

I

Business / First

from
$645*
Updated: 3 hours ago

Charlotte (CLT)to

Grand Cayman (GCM)
03/12/25 - 03/19/25

Round trip

I

Business / First

from
$1,175*
Updated: 4 hours ago

Philadelphia (PHL)to

Grand Cayman (GCM)
04/18/25 - 04/23/25

Round trip

I

Business / First

from
$1,309*
Updated: 4 hours ago

Chicago (ORD)to

Grand Cayman (GCM)
03/31/25 - 04/05/25

Round trip

I

Business / First

from
$1,374*
Updated: 3 hours ago

Boston (BOS)to

Grand Cayman (GCM)
03/13/25 - 03/19/25

Round trip

I

Business / First

from
$857*
Updated: 1 hour ago

Columbus (CMH)to

Grand Cayman (GCM)
03/03/25 - 03/07/25

Round trip

I

Business / First

from
$908*
Updated: 6 hours ago

Los Angeles (LAX)to

Grand Cayman (GCM)
04/16/25 - 04/23/25

Round trip

I

Business / First

from
$2,169*
Updated: 1 hour ago

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

Find deals on flights to Cayman Islands

Dallas (DFW)to

Grand Cayman (GCM)
07/16/25 - 07/23/25

Round trip

I

Economy

from
$585*
Updated: 46 minutes ago

Miami (MIA)to

Grand Cayman (GCM)
06/25/25 - 07/01/25

Round trip

I

Economy

from
$325*
Updated: 4 hours ago

Charlotte (CLT)to

Grand Cayman (GCM)
08/05/25 - 08/12/25

Round trip

I

Economy

from
$535*
Updated: 1 hour ago

Philadelphia (PHL)to

Grand Cayman (GCM)
08/09/25 - 08/14/25

Round trip

I

Economy

from
$600*
Updated: 7 hours ago

Chicago (ORD)to

Grand Cayman (GCM)
07/12/25 - 07/19/25

Round trip

I

Economy

from
$635*
Updated: 6 hours ago

Columbus (CMH)to

Grand Cayman (GCM)
07/18/25 - 07/31/25

Round trip

I

Economy

from
$538*
Updated: 4 hours ago

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

Discover best flight deals to Cayman Islands