Flights to Panama with American Airlines

Popular flights with American Airlines

  • Philadelphia (PHL)to

    Panama City (PTY)
    04/22/25 - 04/29/25
    from
    $499*
    Updated: 2 hours ago
    Round trip
    I
    Economy

    Philadelphia (PHL)to

    Panama City (PTY)
    05/13/25 - 05/20/25
    from
    $499*
    Updated: 2 hours ago
    Round trip
    I
    Economy

    Charlotte (CLT)to

    Panama City (PTY)
    04/28/25 - 05/05/25
    from
    $467*
    Updated: 9 hours ago
    Round trip
    I
    Economy

    Charlotte (CLT)to

    Panama City (PTY)
    05/05/25 - 05/12/25
    from
    $467*
    Updated: 9 hours ago
    Round trip
    I
    Economy

  • New York (NYC)to

    Panama City (PTY)
    02/25/25 - 03/04/25
    from
    $471*
    Updated: 16 minutes ago
    Round trip
    I
    Economy

    New York (NYC)to

    Panama City (PTY)
    02/28/25 - 03/07/25
    from
    $471*
    Updated: 16 minutes ago
    Round trip
    I
    Economy

    Phoenix (PHX)to

    Panama City (PTY)
    05/06/25 - 05/13/25
    from
    $595*
    Updated: 9 hours ago
    Round trip
    I
    Economy

    Phoenix (PHX)to

    Panama City (PTY)
    05/13/25 - 05/20/25
    from
    $595*
    Updated: 9 hours ago
    Round trip
    I
    Economy

  • Raleigh (RDU)to

    Panama City (PTY)
    05/02/25 - 05/09/25
    from
    $455*
    Updated: 8 hours ago
    Round trip
    I
    Economy

    Raleigh (RDU)to

    Panama City (PTY)
    05/07/25 - 05/14/25
    from
    $455*
    Updated: 8 hours ago
    Round trip
    I
    Economy

    New York (JFK)to

    Panama City (PTY)
    05/02/25 - 05/09/25
    from
    $471*
    Updated: 1 hour ago
    Round trip
    I
    Economy

    New York (JFK)to

    Panama City (PTY)
    05/03/25 - 05/10/25
    from
    $471*
    Updated: 1 hour ago
    Round trip
    I
    Economy

  • Saint Louis (STL)to

    Panama City (PTY)
    05/05/25 - 05/12/25
    from
    $469*
    Updated: 7 hours ago
    Round trip
    I
    Economy

    Saint Louis (STL)to

    Panama City (PTY)
    05/06/25 - 05/13/25
    from
    $469*
    Updated: 7 hours ago
    Round trip
    I
    Economy

    Tampa (TPA)to

    Panama City (PTY)
    04/24/25 - 05/01/25
    from
    $433*
    Updated: 52 minutes ago
    Round trip
    I
    Economy

    Tampa (TPA)to

    Panama City (PTY)
    04/15/25 - 04/22/25
    from
    $433*
    Updated: 52 minutes ago
    Round trip
    I
    Economy

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

Flights to Panama with American Airlines

Business Class flights to Panama 

Miami (MIA)to

Panama City (PTY)
06/13/25 - 06/22/25

Round trip

I

Business / First

from
$1,224*
Updated: 17 hours ago

Dallas (DFW)to

Panama City (PTY)
05/09/25 - 05/16/25

Round trip

I

Business / First

from
$1,213*
Updated: 14 hours ago

Philadelphia (PHL)to

Panama City (PTY)
03/01/25 - 03/04/25

Round trip

I

Business / First

from
$1,059*
Updated: 12 hours ago

Charlotte (CLT)to

Panama City (PTY)
06/03/25 - 06/08/25

Round trip

I

Business / First

from
$1,175*
Updated: 13 hours ago

New York (NYC)to

Panama City (PTY)
05/03/25 - 05/13/25

Round trip

I

Business / First

from
$1,170*
Updated: 13 hours ago

Phoenix (PHX)to

Panama City (PTY)
05/08/25 - 05/18/25

Round trip

I

Business / First

from
$1,255*
Updated: 10 hours ago

Chicago (ORD)to

Panama City (PTY)
05/28/25 - 06/01/25

Round trip

I

Business / First

from
$1,339*
Updated: 12 hours ago

Orlando (MCO)to

Panama City (PTY)
05/30/25 - 06/02/25

Round trip

I

Business / First

from
$988*
Updated: 12 hours ago

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

Find deals on flights to Panama

Miami (MIA)to

Panama City (PTY)
01/01/26 - 01/08/26

Round trip

I

Economy

from
$399*
Updated: 17 hours ago

Dallas (DFW)to

Panama City (PTY)
07/01/25 - 07/15/25

Round trip

I

Economy

from
$504*
Updated: 13 hours ago

Charlotte (CLT)to

Panama City (PTY)
12/06/25 - 12/13/25

Round trip

I

Economy

from
$507*
Updated: 1 hour ago

Tampa (TPA)to

Panama City (PTY)
12/06/25 - 12/13/25

Round trip

I

Economy

from
$513*
Updated: 29 minutes ago

New York (JFK)to

Panama City (PTY)
11/24/25 - 11/29/25

Round trip

I

Economy

from
$893*
Updated: 17 hours ago

Austin (AUS)to

Panama City (PTY)
06/27/25 - 07/11/25

Round trip

I

Economy

from
$558*
Updated: 15 hours ago

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

Discover best flight deals to Panama